SINGLET OXYGEN GENERATION OF PORPHYRINS, CHLORINS, AND PHTHALOCYANINES

Singlet oxygen generation of porphyrins, chlorins, and phthalocyanines.

The production of singlet oxygen was measured indirectly for three classes of photosensitizers: porphyrins (Photofrin II, TPPS4), chlorins (MACE, DACE), and a phthalocyanine (CASPc). Buffered solutions of sensitizers and singlet oxygen acceptors were irradiated with a CW dye laser and the oxygen depletion was monitored electrochemically with a Clark-type microelectrode. A comparison of oxygen-d...

Singlet Oxygen Trapping Porphyrins

Porphyrins and Phthalocyanines for Theranostics

The field of theranostics is growing rapidly as therapeutic regimes are increasingly being integrated and guided by diagnostic practices such as medical imaging. There is some room for discussion about the general definition of a theranostic agent, if there exists such a definition. Is it a diagnostic imaging agent that is used in the context to guide surgical procedures? Or rather, is it a the...

Cross-metathesis reactions of vinyl-chlorins and -porphyrins catalyzed by a "second generation" Grubbs' catalyst.

The first application of olefin cross-metathesis with vinylchlorins and vinylporphyrins using a "second generation" Grubbs' catalyst is reported. Cross-metathesis products were obtained in good yields with high E-stereoselectivity.

Photochemical Transformations Involving Porphyrins and Phthalocyanines

2 1. Introduction Photochemistry of the porphyrins and their relatives has been largely inspired by photosynthetic processes in nature. As a result of this, most current studies generally utilize the chemistry of magnesium and zinc porphyrin analogues. Especially, magnesium tetrapyrrole chelates, i.e. magnesium porphyrins and phthalocyanines have found wide interest. This is primarily related t...